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Metizolam (9 methyl 6h thieno 3.2 f 1.2.4) is a structural derivative of
benzodiazepine in which the benzene ring is replaced by a
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With the chemical Molecular Formula: C17H15ClN4S
Thiophene is an aromatic five-membered ring (triazolo 4.3 to 1.4) with one sulfur atom.
Metizolam contains a thiophene ring fused to a diazepine ring,
a seven-membered ring with the two nitrogen components at R 1 and R 4.
This forms the (ethyl 9 methyl 6h) of Metizolam.
An ethyl chain is bonded to this bicyclic structure at R 7,
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At Metizolam, the benzene ring has been replaced by a thiophene
ring connected to R1 and R2 of this diazepine ring.
As a result, Metizolam belongs to the thienotriazolobenzodiazepines, an antidepressant.
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General info about Metizolam
Metizolam was developed in 1983 in Japan (brand name Etilaam)
for a number of neurological conditions, including insomnia and anxiety.
Ultimately, it turned out that in chronic haematomas in the
brain after neurosurgery Metizolam could also be helpful.
It appears to be an antagonist of platelet activating (PAF) receptors in the brain.
Metizolam is a thienodiazepine derivative which is a benzodiazepine analog.
Metizolam ensures that the whole body relaxes and reduces anxiety.
Many users do not give reviews but get very sleepy from Metizolam.
♦ 1 mg Metizolam is equivalent to 10 mg diazepam.
Research has shown that Metizolam has a half-life
of about 3.5 hours and has an effect about 6 times stronger than diazepam.
The effect of Metizolam starts after 30-60 minutes and has a peak
after 3-4 hours and the effect usually lasts for 6-8 hours.
The active metabolite of Metizolam, alphahydroxyMetizolam,
however, has an elimination half-life of about 8 hours.
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